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Allergic Rhinitis (Nasal Allergies, Hay Fever)

Allergic rhinitis, commonly known as hay fever, is the most common allergic disorder affecting approximately 20% to 25% of the population. The most frequent symptoms are nasal congestion, itchy runny nose, itchy runny eyes, and fits of sneezing. Other frequently accompanying symptoms are headache around the eye area, drainage in the throat, fatigue, and lack of energy. There can also be intense itching of the throat and deep in the ears. The term hay fever is really a misnomer in that it is rarely due to hay, and there is no fever associated with it even though patients feel feverish as the result of the effects of histamine on the blood vessels causing them to dilate and feel warm.

Allergic respiratory symptoms are a result of histamine release along with other chemicals that are either preformed or formed in allergy cells as a result of an antigen antibody interaction.

The job of the allergist is to determine whether the above symptoms are due to allergies or not. Allergic rhinitis is typically classified as seasonal (intermittent) or perennial (persistent), or both. Frequent triggers of true hay fever symptoms include the pollens from grass, tree, and weeds, house dust mite, mold spores, and animal dander. If the above described symptoms are triggered by cleaning one’s home, playing with pets, mowing the grass, etc., then there is high likelihood that symptoms are due to allergies. If your doctor cannot make a correlation of your symptoms with the above triggers, then you need to start thinking outside the allergy box.

The correct diagnostic term for nasal symptoms not due to allergies is non-allergic or vasomotor rhinitis. We don’t understand the mechanism of this condition totally. As the name applies, it is not on an allergic basis, that is to say an antigen antibody interaction. Triggers of non-allergic rhinitis include irritants such as tobacco smoke, chemical odors, cold air, strong perfumes, etc.

Other conditions to consider in people with symptoms of a stuffy nose are hypothyroidism (low thyroid), nasal polyps, tumors (cancer), foreign bodies, infection, and deviated nasal septum. There is also another condition that goes by the acronym N.A.R.E.S. which stands for nonallergic rhinitis with eosinophilia. This means that a person can have all of the symptoms of allergies but are skin test negative, and yet paradoxically have an abundance of allergy cells called eosinophils in their nasal mucus. This condition responds nicely to intranasal steroid sprays.

The nose is the center of the universe to an allergist. If a person does not describe classic nasal symptoms, and for instance only complains that ears or eyes bother them, then the likelihood of symptoms being due to allergies is lessened.

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Needle-Free Option for Severe Allergic Reactions Expanded for Use in Children

Doctors at the Oklahoma Allergy and Asthma Clinic call the FDA approval a game-changer

Parents now have a needle-free, life-saving option should their child experience a severe allergic reaction.

The U.S. Food and Drug Administration this week approved neffy nasal spray in a one milligram dose, expanding its use to younger children. Neffy is a nasal spray for the emergency treatment of severe allergic reactions, including anaphylaxis. The FDA action means neffy may now be used in children ages four years or older, weighing between 33 and 66 pounds.

The drug was originally approved as a two-milligram dose for individuals over 66 pounds back in August of 2024.

“The approval of one milligram neffy is a game-changer for our young patients who suffer from severe allergies and asthma-related anaphylaxis,” said Dr. Maya Gharfeh, allergy and asthma specialist at the Oklahoma Allergy & Asthma Clinic. “As a physician, I’ve seen firsthand the hesitation and fear that children and parents experience when faced with the need for an epinephrine injection. With neffy, we now have a needle-free alternative that can provide the same life-saving benefits in a less intimidating way.”

Neffy provides a convenient and effective solution for managing life-threatening allergic reactions without the need for injections.

“Anaphylaxis is life-threatening, and some people, particularly children, may delay or avoid treatment due to fear of injections,” said Dr. Kelly Stone, Associate Director of the Division of Pulmonology, Allergy, and Critical Care at the FDA’s Center for Drug Evaluation and Research. “The availability of epinephrine nasal spray may reduce barriers to rapid treatment of anaphylaxis.”

According to the the Asthma and Allergy Foundation of America, anaphylaxis occurs in about one in 50 Americans and some estimates place it as high as one in 20.

“As allergy specialists, we know that some parents of small children may hesitate to use traditional epinephrine auto-injectors due to needle anxiety. Now, we have another option for them,” Gharfeh added.

Neffy is expected to be available in the United States by the end of May 2025.

For more information about the Oklahoma Allergy & Asthma Clinic, visit at www.oklahomaallergy.com or for an appointment, call 405-235-0040.

The post Needle-Free Option for Severe Allergic Reactions Expanded for Use in Children appeared first on Oklahoma Allergy and Asthma Clinic.

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