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Pharmacologic (Medicine) Treatment for Nasal Allergies

Pharmacologic (Medicine) Treatment for Nasal Allergies

Antihistamines which are prescribed for the treatment of allergies fall into two categories, first generation and second generation. The first generation antihistamines are the oldest ones and date back several decades. Their chemical makeup is such that it gets into brain tissue very easily and, therefore, cause the most side effects. Almost all first generation antihistamines are over-the-counter. Examples are Benadryl, Chlor-Trimeton, Tavist, Allerest, etc.

The more recent advance in antihistamines, the so-called second generation antihistamines, are made up so that they do not get into brain tissue so easily and, therefore, cause less drowsiness. Examples are Claritin, Clarinex, Allegra, Zyrtec, Xyzal, and even Astelin and Patanase which are unique in that they are the only nasal spray antihistamines.

Antihistamines can be combined with decongestants. Pseudoephedrine and Phenylephrine are examples of decongestants that can be combined with antihistamines. Their purpose is to alleviate nasal and sinus congestion which can be a significant part of allergic symptoms in many people. Allegra-D, Clarinex-D, Zyrtec-D and Claritin-D are examples.

Singulair (classified as anti-inflammatory) is another category of medication shown to be effective for both nasal allergies and asthma. If the leukotriene pathway of inflammation is involved in a person’s allergies, then Singulair can be highly effective.

Intranasal steroid sprays are probably the mainstay of treatment for nasal allergies. Examples include Nasonex, Nasacort AQ, Rhinocort AQ, Flonase, Veramyst, Nasarel, Beconase AQ, and Vancenase AQ, and the most recent Omnaris. These are corticosteroids and are true antiinflammatory medicines to combat allergic inflammation. They are universally considered the drug of choice for nasal allergies. They are topically active and, therefore, poorly absorbed, so there is very little risk of systemic steroid side effects from them.

Another category of medication is the anti-cholinergic Atrovent (ipratropium) which is basically a drying agent for people who have significant runny noses.

NasalCrom (Cromolyn Sodium) is an older medication which supposedly prevents histamine from coming out of the allergy cell. It is not a very effective treatment and can be purchased over-the-counter.

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What Is an Allergy?

An allergy is when your immune system reacts to a foreign substance, called an allergen. This reaction causes specific clinical symptoms. The allergen could be something you eat, inhale into your lungs, inject into your body, or touch.

An allergic reaction can cause coughing, sneezing, hives, rashes, itchy eyes, a runny nose, swelling, and a scratchy throat. In severe cases, it can cause low blood pressure, breathing trouble, asthma attacks, and even death if not treated promptly and appropriately.

There is no cure for allergies. You can manage allergies with proper education, prevention, and medical treatment.

Allergies are among the country’s most common, but overlooked, diseases. 

How Common Are Allergies?

More than 100 million people in the U.S. experience various types of allergies each year. Common examples include seasonal allergies, eczema, and food allergies.

Nearly 1 in 3 U.S. adults and more than 1 in 4 U.S. children have a seasonal allergy, eczema, or food allergy. 

How Many People Seek Medical Care for Allergies?

Allergic conditions are one of the most common health issues affecting children in the U.S.

Each year in the U.S., it is estimated that anaphylaxis (a severe allergic reaction) to food results in 90,000 emergency room visits. 

How Many People Die from Allergies?

The most common triggers for anaphylaxis are medicines, food, and insect stings.5 Medicines cause most allergy-related deaths.

Older adults in the U.S. have the highest rates of death due to allergic reactions to medicines, food, or unknown allergens.

The post What Is an Allergy? appeared first on Oklahoma Allergy and Asthma Clinic.

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