Search
× Search

Non-Allergic Rhinitis (Vasomotor)

Non-Allergic Rhinitis (Vasomotor)

Non-allergic rhinitis is a chronic condition that can occur at any age but is more common in adults. The most common symptoms are nasal congestion, post-nasal drainage, and headache, although runny nose, sneezing and itching of the nose may occur in some non-allergic individuals. Many non-allergic patients have recurrent sinusitis and middle ear infections or middle ear fluid collection.

Initial evaluation requires that surgical conditions (growths in the nose, crooked nasal septum, etc.) and general medical conditions (thyroid disease, pregnancy, etc.) are not responsible for the chronic symptoms. We recommend that ever patient have a family practitioner, internist, or pediatrician to follow them for their general medical care. If the history and physical examination are not positive for surgical or general medical problems, the patient most likely has the most common nasal problem of non-allergic or allergic nasal disease.

Non-allergic rhinitis is a very difficult topic to fully understand. The actual defect resulting in the symptoms commonly found is not known. We do know that the difficulty arises in the inability to correctly change the size of blood vessels and the quantity of mucus produced by mucus glands in the nose. Under normal circumstances the nose warms or cools the air entering the nose to 98 degrees F., increases the humidity to at least 80%, and filters unwanted substances resulting in relatively clean air at 98 degrees F. and 80% humidity entering the lungs regardless of current environmental conditions. These changes occur almost instantly with each breath. The non-allergic individual has lost the ability to make the necessary changes either from an ineffective blood vessel and mucus gland controlling mechanism, temperature and humidity sensing mechanism, or both. The end result is inappropriate blood vessel size and/or excess mucus production which can result in nasal congestion, post-nasal drainage, and headaches.

Many individuals with non-allergic nasal disease will have a significant amount of irritation, inflammation, and hyperreactivity in the nose contributing to the persistent, chronic nature of the disease.

Nasal allergy on the other hand usually presents with runny nose, sneezing, and itching but some patients can also have nasal congestion, post-nasal drainage, and headaches. With nasal allergy we usually see definite problems at certain seasons of the year or a correlation with exposures to dust, animal dander, mold or mildew exposures and in some patients’ extreme reactions to certain foods. Allergy symptoms also involving the eyes usually are redness, itching and watering of the eyes.

It is possible for an individual to have problems with both non-allergic rhinitis and allergic rhinitis, and this makes the problems at times more difficult to clearly diagnose and treat.

Several tests can be used to differentiate non-allergic rhinitis from allergic rhinitis. Skin testing, as one might expect, displays positivity in patients with allergic rhinitis, whereas a negative skin test will be obtained in patients with non-allergic rhinitis. In addition, the blood IgE levels and eosinophils (the allergy cell) are elevated in patients with allergic rhinitis but not in non-allergic rhinitis.

Non-allergic rhinitis often is triggered by drafts, temperature changes (especially cold air), by scented cosmetics (both men’s and women’s cosmetics), by cigarette and tobacco smoke, as well as fireplace smoke, scented or perfumed soaps. Many types of aerosol sprays, even scented deodorants can cause problems. Paint fumes, insecticides, bug sprays,
varnishes, and even the odor from new clothing, carpeting or furniture can cause problems. Kerosene, lighter fluids, oil and gas fumes can cause problems. House dust may act as an irritant, and should be avoided.

Do not overuse over-the-counter decongestant sprays or nose drops because these can cause “rebound” nasal congestion. All nasal decongestant sprays should be discontinued following 3 days of continuous use. Medications will be prescribed to help with this problem. A good part of the treatment is avoiding known problems and exposures, and working by trial and error to find medications that work best in your case. Medications that may be tried include: Astelin© nasal spray, decongestants, decongestant-antihistamine combinations, intranasal steroid sprays, and possibly an atropine-derivative nasal spray (Atrovent©).

Recent News

SuperUser Account
/ Categories: News

Important Recall Notice for AIRSUPRA Inhalation Aerosol

AstraZeneca Pharmaceuticals LP, the maker of the inhalation medication AIRSUPRA® (albuterol and budesonide) aerosol, has initiated a voluntary recall for their product. This recall is effective immediately and involves multiple product lots. The recalled inhalers might not work properly.

Reason for Recall:

A defect in the delivery system of these inhalers has been identified, which may hinder the proper administration of the medication needed for effective asthma control.

Product Details:

Product Name: AIRSUPRA (albuterol and budesonide) inhalation aerosol 

Strength: 90 mcg/80 mcg per inhalation 

Packaging Types:

120-inhalation canister (NDC 0310-9080-12) 

 28-inhalation canister (NDC 0310-9080-28) 

Recall Number:  D-0444-2025 

Affected Lot Numbers:

For 120-inhalation canisters: Lots: 6270044C00, 6270040D00, 6270034E00, Exp Date 10/2026; 6270053C00, 6270045C00, 6270047C00, 6270056C00, 6270052C00, 6270063E00 Exp 11/30/2026; 6270064C00, 6270071D00, 6270075D00, 6270075F00 Exp Date 12/31/2026; 6270107C00, Exp Date 9/30/2027  

For 28-inhalation canisters: Lot 6270019E00, Exp Date 7/31/2025; 6270021D00, Exp 8/31/2025; 6270095C00, Exp 2/28/2026

Rx only, Manufactured for: AstraZeneca Pharmaceuticals LP, Wilmington, DE 19850, By: AstraZeneca Dunkerque Production (AZDP), Dunkerque, France, Product of France

What You Should Do:

Patients and users are advised not to use the inhalers associated with the affected lots. Please contact your pharmacy or healthcare provider as soon as possible to discuss alternative treatment options. Contact the dispensing pharmacy or AstraZeneca for return processing information.

If you are a current patient of the Oklahoma Allergy and Asthma Clinic affected by this recall, please give us a call at 405-235-0040.  

Recall Contact Information:

For product questions, to report an adverse event or side effect, or to report a product quality issue, you can contact the AstraZeneca Information Center by phone at:

1-800-236-9933 (M-F, 8AM-6PM ET, excluding holidays)

Or you can report a product quality issue online: https://contactazmedical.astrazeneca.com/content/astrazeneca-champion/global/en/amp-form.html

For more information on this recall, please visit: https://www.accessdata.fda.gov/scripts/ires/?Event=96857

The post Important Recall Notice for AIRSUPRA Inhalation Aerosol appeared first on Oklahoma Allergy and Asthma Clinic.

Previous Article Needle-Free Option for Severe Allergic Reactions Expanded for Use in Children
Next Article Main Clinic Update
Print
45
Terms Of UsePrivacy StatementCopyright 2026 by Oklahoma Allergy and Asthma Clinic
Back To Top